CLINICAL TESTS & TRIALS

The live bacteria in our formulas have over 50 clinical trials to support their effectiveness. Browse our research library to discover a selection of them, and see the science behind the strains and ingredients.

Does coenzyme Q10 supplementation improve fertility outcomes in women undergoing assisted reproductive technology procedures? A systematic review and meta-analysis of randomized-controlled trials

CoQ10 Supplementation Boosts Pregnancy Rates in Female Infertility.

https://link.springer.com/

Effects of L-carnitine supplementation for women with polycystic ovary syndrome: a systematic review and meta-analysis

L-Carnitine's Potential Impact on PCOS Symptoms.

https://www.ncbi.nlm.nih.gov/pmc/

Antioxidants for female subfertility

The effect of Antioxidants on Subfertility.

https://pubmed.ncbi.nlm.nih.gov/

Female Fertility and the Nutritional Approach: The Most Essential Aspects

Diet and Lifestyle's Impact on Female Fertility.

https://www.ncbi.nlm.nih.gov/

Dietary Folate and Reproductive Success Among Women Undergoing Assisted Reproduction

Folate and Success in Assisted Reproduction.

https://www.ncbi.nlm.nih.gov/pmc/

Role of L-carnitine in female infertility

L-Carnitine's Impact on Female Infertility.

https://www.ncbi.nlm.nih.gov/

Micronutrient Deficiency in Women Living in Industrialized Countries During the Reproductive Years: Is there a Basis for Supplementation with Multiple Micronutrients?

The Impact of Micronutrient Supplementation on Women's Fertility.

https://www.walshmedicalmedia.com/

The Microbiome, an Important Factor That Is Easily Overlooked in Male Infertility.

Unnoticed Role of Microbiome in Male Infertility.

https://www.frontiersin.org/articles/

Male factor subfertility: possible causes and the impact of nutritional factors

Understanding Male Subfertility and Nutritional Impact.

https://pubmed.ncbi.nlm.nih.gov/

Dietary fat and semen quality among men attending a fertility clinic

The Association Between Dietary Fats and Semen Quality.

https://pubmed.ncbi.nlm.nih.gov/

Dietary patterns and semen quality in young men

Diet and Semen Quality in Young Men.

https://pubmed.ncbi.nlm.nih.gov/

High-energy diets: a threat for male fertility?

The Decline of Male Fertility: Impact of High-Energy Diets.

https://pubmed.ncbi.nlm.nih.gov/

Effects of vitamin E and vitamin C on male infertility: a meta-analysis

Effects of vitamin E and vitamin C on male infertility.

https://pubmed.ncbi.nlm.nih.gov/

The association between iodine intake and semen quality among fertile men in China

Iodine's Impact on Semen Quality.

https://bmcpublichealth.biomedcentral.com/

Diet and Nutritional Factors in Male (In)fertility—Underestimated Factors

Male Infertility and Dietary Factors.

https://www.ncbi.nlm.nih.gov/

The Role of Dietary Nutrients in Male Infertility: A Review

The Role of Dietary Nutrients in Male Infertility.

https://pubmed.ncbi.nlm.nih.gov/

The role of carnitine in male infertility

The role of carnitine in male infertility.

https://onlinelibrary.wiley.com/

Food intake and social habits in male patients and its relationship to intracytoplasmic sperm injection outcomes

Positive influence of fruits and cereals on sperm motility.

https://pubmed.ncbi.nlm.nih.gov/

Nutritional modifications in male infertility: a systematic review covering 2 decades

Overview of male infertility and nutrition.

https://www.ncbi.nlm.nih.gov/

Characteristics of the gut microbiota in women with premenstrual symptoms: A cross-sectional study

Gut health and PMS

https://www.ncbi.nlm.nih.gov/

Symptomatology of irritable bowel syndrome and inflammatory bowel disease during the menstrual cycle

IBS and IBD during the menstrual cycle

https://www.ncbi.nlm.nih.gov/

A pilot study to assess the effect of a fibre and mineral formulation on satiety and satiation when taken as part of a calorie restriction diet in overweight and obese women

The effect of a fibre and mineral formulation on satiety and satiation.

https://www.sciencedirect.com/

Efficacy of vitamin B-6 in the treatment of premenstrual syndrome: systematic review

Vitamin B-6 and PMS

https://www.ncbi.nlm.nih.gov/

Menstrual cycle effects on the metabolism of tryptophan loads

Tryptophan and the menstrual cycle

https://pubmed.ncbi.nlm.nih.gov/

Acute tryptophan depletion aggravates premenstrual syndrome

Tryptophan and premenstrual syndrome

https://www.sciencedirect.com/

A placebo-controlled clinical trial of L-tryptophan in premenstrual dysphoria

L-tryptophan and PMS

https://pubmed.ncbi.nlm.nih.gov/

Clinical evaluation of the pharmacological impact of ashwagandha root extract on sleep in healthy volunteers and insomnia patients: A double-blind, randomized, parallel-group, placebo-controlled study

Impact of ashwagandha root extract on sleep

https://pubmed.ncbi.nlm.nih.gov/

Efficacy and Safety of Ashwagandha (Withania somnifera) Root Extract for Improvement of Sexual Health in Healthy Women: A Prospective, Randomized, Placebo-Controlled Study

Ashwagandha and female health

https://www.ncbi.nlm.nih.gov/pmc/articles/

Menstrual cycle and exercise effects on protein catabolism

The purpose of this investigation was to determine whether exercise at different times of the menstrual cycle alters protein catabolism.

https://pubmed.ncbi.nlm.nih.gov/

Zinc treatment prevents dysmenorrhea

Zinc and Menstrual Cramps

https://pubmed.ncbi.nlm.nih.gov/

The Efficacy of Zinc Administration in the Treatment of Primary Dysmenorrhea

The impact of Zinc on period paid

https://www.ncbi.nlm.nih.gov/

The role of vitamin C in iron absorption

https://pubmed.ncbi.nlm.nih.gov/

The effects of Curcumin in pain relief in women diagnosed with primary dysmenorrhea: A triple blinded, placebo-controlled, phase II, randomized clinical trial protocol.

The effects of Curcumin in pain relief in women.

https://journal.ppcr.org/

Effects of curcumin on menstrual pattern, premenstrual syndrome, and dysmenorrhea: A triple-blind, placebo-controlled clinical trial

Effects of curcumin on PMS

https://pubmed.ncbi.nlm.nih.gov/

Curcumin attenuates severity of premenstrual syndrome symptoms: A randomized, double-blind, placebo-controlled trial

This study was done to evaluate the effects of curcumin on severity of PMS symptoms.

pubmed.ncbi.nlm.nih.gov

Regular chicory intake improved blood glucose, lipid profile and serum insulin in people with prediabetes and diabetes

PREBIOTIC BLEND

pubmed.ncbi.nlm.nih.gov

Daily chicory intake improved Bifidobacterium (beneficial bacteria) content of the gut

PREBIOTIC BLEND

pubmed.ncbi.nlm.nih.gov

Daily chicory root fibre intake reduced gas retention by 22%

PREBIOTIC BLEND

www.ncbi.nlm.nih.gov

Psyllium effective treatment for ulcerative colitis

PREBIOTIC BLEND

pubmed.ncbi.nlm.nih.gov

Reduced flatulence with psyllium husk

PREBIOTIC BLEND

pubmed.ncbi.nlm.nih.gov

Psyllium husk increases faecal weight

PREBIOTIC BLEND

pubmed.ncbi.nlm.nih.gov

Gut feelings: A randomised, triple-blind, placebo-controlled trial of probiotics for depressive symptoms.

For Mind & Mood

pubmed.ncbi.nlm.nih.gov

Daily ashwagandha supplementation can balance hormones

www.ncbi.nlm.nih.gov

Tryptophan is a precursor to serotonin (gut-brain axis)

www.ncbi.nlm.nih.gov

Ashwagandha is an adaptogen that can help relieve stress (reduce cortisol) and anxiety

www.ncbi.nlm.nih.gov

A randomized controlled trial to test the effect of multispecies probiotics on cognitive reactivity to sad mood.

For Mind & Mood

pubmed.ncbi.nlm.nih.gov

Psyllium as effective as dietitian led low FODMAP diet in treatment of faecal incontinence

PREBIOTIC BLEND

pubmed.ncbi.nlm.nih.gov

Inositol increases insulin sensitivity and protects against diabetes and PCOS

www.ncbi.nlm.nih.gov

Psyllium reduces constipation

PREBIOTIC BLEND

pubmed.ncbi.nlm.nih.gov

Inositol particularly effective in those suffering with PCOS

www.pubmed.ncbi.nlm.nih.gov

Inositol may balance hormones and increase fertility

www.pubmed.ncbi.nlm.nih.gov

Hormonal balancing effects of maca root (rodent study)

www.ncbi.nlm.nih.gov

Maca root supplementation may be beneficial as a hormonal balancing treatment during menopause, male aging and sexual dysfunction

www.sciencedirect.com

Taurine is a therapeutic agent that can enhance health, particularly heart health

www.ncbi.nlm.nih.gov

Ginseng can regulate the HPA axis and positively influence various hormones

www.ncbi.nlm.nih.gov

Efficacy and Safety of Lactobacillus plantarum DSM 9843 (LP299V) in the prevention of Antibiotic-Associated Gastrointestinal symptoms in children – Randomized, double-blind, placebo-controlled study

This clinical trial includes Lactobacillus plantarum DSM 9843. The live bacteria in KÄLLA FOR RELIEF.

sciencedirect.com

Ginseng can enhance quality of life by balancing hormones of middle aged women (Swedish study)

www.pubmed.ncbi.nlm.nih.gov

Probiotic Lactobacillus Plantarum 299v decreases kynurenine concentration and improves cognitive functions in patients with major depression: A double-blind, randomized, placebo controlled study

This clinical trial includes Lactobacillus plantarum DSM 9843. The live bacteria in KÄLLA FOR RELIEF.

sciencedirect.com

Potential glucoregulatory actions of ginseng and adaptogen

www.pubmed.ncbi.nlm.nih.gov

The Effect of Lactobacillus plantarum 299v on Iron Status and Physical Performance in Female Iron-Deficient Athletes: A Randomized Controlled Trial

This clinical trial includes Lactobacillus plantarum DSM 9843. The live bacteria in KÄLLA FOR RELIEF.

mdpi.com

Coenzyme Q10 can influence energy producing hormones, particularly thyroid hormone

www.ncbi.nlm.nih.go

Fewer community-acquired colds with daily consumption of Lactiplantibacillus plantarum HEAL9 and Lacticaseibacillus paracasei 8700:2. A randomized, placebo- controlled clinical trial.

This clinical trial includes Lactiplantibacillus plantarum DSM 15312 and Lacticaseibacillus paracasei DSM 13434. The live bacteria in KÄLLA FOR IMMUNE HEALTH

academic.oup.com

Probiotic Lactobacillus Plantarum 299v decreases kynurenine concentration and improves cognitive functions in patients with major depression: A double-blind, randomized, placebo controlled study

Magnesium interacts with parathyroid hormone and estrogen

www.ncbi.nlm.nih.go

Effects of Lactobacillus plantarum and Lactobacillus paracasei on the Peripheral Immune Response in Children with Celiac Disease Autoimmunity: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial. of Common Cold

This clinical trial includes Lactiplantibacillus plantarum DSM 15312 and Lacticaseibacillus paracasei DSM 13434. The live bacteria in KÄLLA FOR IMMUNE HEALTH

mdpi.com

The efficacy and safety of probiotics in patients with irritable bowel syndrome: Evidence based on 35 randomized controlled trials.

This review includes Lactobacillus plantarum DSM 9843. The live bacteria in KÄLLA FOR RELIEF.

sciencedirect.com

A Systematic Review and Meta-Analysis on the Effects of Probiotic Species on Iron Absorption and Iron Status.

This review includes Lactobacillus plantarum DSM 9843. The live bacteria in KÄLLA FOR RELIEF.

mdpi.com

A systematic review and meta-analysis: probiotics in the treatment of irritable bowel syndrome.

This review includes Lactobacillus plantarum DSM 9843. The live bacteria in KÄLLA FOR RELIEF.

link.springer.com

Intake of Lactobacillus plantarum Reduces Certain Gastrointestinal Symptoms During Treatment With Antibiotics

This clinical trial includes Lactobacillus plantarum DSM 9843. The live bacteria in KÄLLA FOR RELIEF.

journals.lww.com

Clinical trial: Lactobacillus plantarum 299v (DSM 9843) improves symptoms of irritable bowel syndrome

This clinical trial includes Lactobacillus plantarum DSM 9843. The live bacteria in KÄLLA FOR RELIEF.

ncbi.nlm.nih.gov

A controlled, double-blind, randomized study on the efficacy of Lactobacillus plantarum 299V in patients with irritable bowel syndrome

This clinical trial includes Lactobacillus plantarum DSM 9843. The live bacteria in KÄLLA FOR RELIEF.

pubmed.ncbi.nlm.nih.gov

Alteration of intestinal microflora is associated with reduction in abdominal bloating and pain in patients with irritable bowel syndrome

This clinical trial includes Lactobacillus plantarum DSM 9843. The live bacteria in KÄLLA FOR RELIEF.

pubmed.ncbi.nlm.nih.gov

Randomised, double-blind and placebo-controlled study using new probiotic lactobacilli for strengthening the body immune defence against viral infections

This clinical trial includes Lactiplantibacillus plantarum DSM 15312 and Lacticaseibacillus paracasei DSM 13434. The live bacteria in KÄLLA FOR IMMUNE HEALTH

pubmed.ncbi.nlm.nih.gov

Intake of Lactiplantibacillus plantarum HEAL9 reduces the inflammatory markers soluble fractalkine and CD163 during acute stress: A randomized, double blind, placebo-controlled study

This clinical trial includes Lactiplantibacillus plantarum DSM 15312. The live bacteria in KÄLLA FOR REPAIR.

sciencedirect.com

Differential effect on cell-mediated immunity in human volunteers after intake of different lactobacilli

This clinical trial includes Lactiplantibacillus plantarum DSM 15312 and Lacticaseibacillus paracasei DSM 13434. The live bacteria in KÄLLA FOR IMMUNE HEALTH

ncbi.nlm.nih.gov

Stress matters: Randomized controlled trial on the effect of probiotics on neurocognition.

For Mind & Mood

pubmed.ncbi.nlm.nih.gov

The effects of probiotics on risk and time preference.

For Mind & Mood

wageningenacademic.com

Psychobiotics for Patients with Chronic Gastrointestinal Disorders Having Anxiety or Depression Symptoms.

For Mind & Mood

https://pubmed.ncbi.nlm.nih.gov/34140777/

Probiotic Lactobacillus Plantarum 299v decreases kynurenine concentration and improves cognitive functions in patients with major depression: A double-blind, randomized, placebo controlled study

This clinical trial includes Lactobacillus plantarum DSM 9843. The live bacteria in KÄLLA FOR RELIEF.

wageningenacademic.com

Probiotics as a treatment for prenatal maternal anxiety and depression: a double-blind randomized pilot trial.

For Mind & Mood

pubmed.ncbi.nlm.nih.gov

Probiotics-induced changes in gut microbial composition and its effects on cognitive performance after stress: exploratory analyses.

For Mind & Mood

pubmed.ncbi.nlm.nih.gov

Differential effect on cell-mediated immunity in human volunteers after intake of different lactobacilli

This clinical trial includes Lactobacillus plantarum DSM 9843. The live bacteria in KÄLLA FOR RELIEF.

ncbi.nlm.nih.gov

Randomized, Double Blind and Placebo Controlled Study Using a Combination of Two Probiotic Lactobacilli to Alleviate Symptoms and Frequency of Common Cold

This clinical trial includes Lactiplantibacillus plantarum DSM 15312 and Lacticaseibacillus paracasei DSM 13434. The live bacteria in KÄLLA FOR IMMUNE HEALTH

scirp.org

Evaluation of the efficacy of Lactobacillus plantarum HEAL9 and Lactobacillus paracasei 8700:2 on aspects of common cold infections in children attending day care: a randomised, double-blind, placebo-controlled clinical study

This clinical trial includes Lactiplantibacillus plantarum DSM 15312 and Lacticaseibacillus paracasei DSM 13434. The live bacteria in KÄLLA FOR IMMUNE HEALTH

pubmed.ncbi.nlm.nih.gov